Academic Literature For Curcumin

The following published studies inform the therapies and protocols described on this page.

1. Efficacy and safety of curcumin in combination with paclitaxel in patients with advanced, metastatic breast cancer: A comparative, randomized, double-blind, placebo-controlled clinical trial
   Saghatelyan T, Tananyan A, Janoyan N, et al. Phytomedicine. 2020;70:153218.
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2. Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
   Bayet-Robert M, Kwiatkowski F, Leheurteur M, et al. Cancer Biol Ther. 2010;9(1):8-14.
   DOI Link PubMed Abstract
3. Curcumin’s effect in advanced and metastatic breast cancer patients treated with first or second-line docetaxel: A randomized trial
   Judith F, Kwiatkowski F, Durando X, et al. Health Sci Rep. 2024;7(9):e70052.
   DOI Link PubMed Abstract
4. A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc) in patients with locally advanced or metastatic cancer
   Greil R, Greil-Ressler S, Weiss L, et al. Cancer Chemother Pharmacol. 2018;82:695-706.
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5. The new combination docetaxel, prednisone and curcumin in patients with castration-resistant prostate cancer: a pilot phase II study
   Mahammedi H, Planchat E, Pouget M, et al. Oncology. 2016;90:69-78.
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6. Phase II trial of curcumin in patients with advanced pancreatic cancer
   Dhillon N, Aggarwal BB, Newman RA, et al. Clin Cancer Res. 2008;14(14):4491-4499.
   DOI Link PubMed Abstract
7. Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors
   Panahi Y, Saadat A, Beiraghdar F, Sahebkar A. Phytother Res. 2014;28(10):1461-1467.
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8. Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials
   Nørskov NP, Bruhn S, Johansen AZ, et al. Pharmaceutics. 2023;15(4):1275.
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9. Curcumin as a complementary treatment in oncological therapy: a systematic review
   Jansen R, Lamers M, Verhoeven R, et al. Eur J Clin Pharmacol. 2024;80:1765-1781.
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10. Curcumin combined with FOLFOX chemotherapy is safe and tolerable in patients with metastatic colorectal cancer in a randomized phase IIa trial
    Howells LM, Iwuji COO, Irving GRB, et al. J Nutr. 2019;149(7):1133-1139.
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